Sayara Yamanobe

The head of the Aoyama Pharmaceutical research lab in Sayama. Originally researching bacteria, she discovered one that could be the key to cloning, she moved on to conduct illegal cloning experiments aiming to achieve immortality. She has a sadistic personality, torturing and killing her captives. Sayara is last seen in episode 1 being surrounded by the zombies she created. In episode 3, she is revealed to have been saved by Apos in the last moment, who injected her with a time spore after her body was already considerably mutilated. As a result, she remained forever crippled and waited 21 years until a powered exoskeleton capable of supporting her was invented.

After one last confrontation with Rin and Maeno, she was finally killed by Apos who removed her spore. From Wikipedia.